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Ampio's knee osteoarthritis injection effective in phase 3 trial

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Ampio's knee osteoarthritis injection effective in phase 3 trial

Ampio Pharmaceuticals, Inc.'s knee osteoarthritis injection Ampion met its primary goal in a phase 3 trial with 71% of patients reporting improvement in pain, function and quality of life.

Osteoarthritis is an incurable and progressive disorder of the joints involving degradation of the intra-articular cartilage, joint lining, ligaments and bone.

The patient response in the trial exceeds the physician reported threshold of 30% for a meaningful treatment in severe osteoarthritis of the knee.

On average, patients saw a 53% decrease in pain, 50% improvement in function and a 45% improvement in quality of life.

If approved, Ampion would be the first intra-articular injection to treat osteoarthritis of the knee. Ampion is also a non-opioid treatment.

The company is preparing to submit a biologics license application to the U.S. Food and Drug Administration.