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Mast Therapeutics lays off staff

Mast Therapeutics Inc. laid off some of its employees as part of a cost-cutting measure.

The restructuring is meant to return focus to AIR001, a clinical-stage investigational drug for treating patients with heart failure as a result of preserved ejection fraction.

Mast Therapeutics is exploring opportunities to monetize its Vepoloxamer programs so it could advance AIR001 instead. Vepoloxamer itself is meant to be used in the sickle cell disease and heart failure.