trending Market Intelligence /marketintelligence/en/news-insights/trending/MOx8yTIc1jvB3fC8kRu2vw2 content
Log in to other products

Login to Market Intelligence Platform


Looking for more?

Contact Us

Request a Demo

You're one step closer to unlocking our suite of comprehensive and robust tools.

Fill out the form so we can connect you to the right person.

  • First Name*
  • Last Name*
  • Business Email *
  • Phone *
  • Company Name *
  • City *
  • We generated a verification code for you

  • Enter verification Code here*

* Required

In This List

Sangamo transfers gene therapy SB-525 to co-developer Pfizer

S&P Global Market Intelligence

Cannabis: Hashing Out a Budding Industry


IFRS 9 Impairment How It Impacts Your Corporation And How We Can Help

The Market Intelligence Platform

Sangamo transfers gene therapy SB-525 to co-developer Pfizer

Sangamo Therapeutics Inc. has transferred SB-525 to Pfizer Inc., its partner in developing the gene therapy for treating the bleeding disorder hemophilia A.

As per their agreement, Richmond, Calif.-based Sangamo handled the early- and mid-stage trials of the drug while Pfizer will take charge of the drug's late-stage trial, expected in 2020.

SB-525 is an investigational gene therapy for severe hemophilia A, a genetic bleeding disorder in which the blood does not clot normally due to the absence or low levels of factor VIII, a protein needed to form blood clots.

Sangamo received $25 million as a milestone payment from New York-based pharmaceutical giant Pfizer.

Sangamo is eligible for total milestone payments of up to $300 million for developing and commercializing SB-525 and tiered royalties from the low teens up to 20% of net yearly sales of SB-525. The company will also receive up to $175 million for additional Hemophilia A gene therapies it co-develops with Pfizer.

The U.S. Food and Drug Administration tagged Sangamo-Pfizer's SB-525 as a regenerative medicine advanced therapy in July and gave it orphan-drug and fast-track designations in 2017.

The gene therapy has also received an orphan medicinal product status from the European Medicines Agency.