GlaxoSmithKline PLC said Luc Debruyne is leaving his role as president of the company's vaccines division at the end of 2018.

Debruyne previously served as the general manager of GlaxoSmithKline's Netherlands and Italy operations, as well as senior vice president of the company's pharmaceuticals business in Europe.

The U.K.-based drugmaker appointed Roger Connor, who is president of its global manufacturing and supply unit, to replace Debruyne, effective Sept. 1.

Further, Regis Simard was named president of pharmaceutical supply chain, also effective Sept. 1. Simard joined GlaxoSmithKline in 2005 as a site director in France and is serving as the company's senior vice president for global pharma manufacturing.